USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P35637 USC-OGP 2-DE database:  P35637 P35637 General information about the entry View entry in simple text format Entry name FUS_HUMAN Primary accession number P35637 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=RNA-binding protein FUS; AltName: Full=75 kDa DNA-pairing protein; AltName: Full=Oncogene FUS; AltName: Full=Oncogene TLS; AltName: Full=POMp75; AltName: Full=Translocated in liposarcoma protein;. Gene name Name=FUS Synonyms=TLS Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1149: pI=6.17; Mw=55186 Cross-references UniProtKB/Swiss-Prot P35637; FUS_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name FUS_HUMAN Primary accession number P35637 Secondary accession number(s) Q9H4A8 Sequence was last modified on  June 1, 1994 (version 1) Annotations were last modified on  March 15, 2017 (version 191) Name and origin of the protein Description RecName: Full=RNA-binding protein FUS; AltName: Full=75 kDa DNA-pairing protein; AltName: Full=Oncogene FUS; AltName: Full=Oncogene TLS; AltName: Full=POMp75; AltName: Full=Translocated in liposarcoma protein; Gene name Name=FUS Synonyms=TLS Encoded on Name=FUS; Synonyms=TLS Keywords 3D-structure; Alternative splicing; Amyotrophic lateral sclerosis; Chromosomal rearrangement; Complete proteome; Direct protein sequencing; Disease mutation; DNA-binding; Metal-binding; Methylation; Neurodegeneration; Nucleus; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Repeat; RNA-binding; Zinc; Zinc-finger. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL S62140; AAB27102.1; -; mRNA EMBL S62138; AAB27103.1; ALT_SEQ; mRNA EMBL X71427; CAA50558.1; ALT_SEQ; mRNA EMBL X71428; CAA50559.1; ALT_SEQ; mRNA EMBL AF071213; AAC35285.1; -; Genomic_DNA EMBL AF071213; AAC35284.1; -; Genomic_DNA EMBL AC009088; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC000402; AAH00402.1; -; mRNA EMBL BC002459; AAH02459.1; -; mRNA EMBL AJ295163; CAC15058.1; ALT_TERM; mRNA CCDS CCDS10707.1; -. [P35637-1]; . CCDS CCDS58454.1; -. [P35637-2]; . PIR S33798; S33798; . PIR S33799; S33799; . RefSeq NP_001164105.1; NM_001170634.1. [P35637-2]; . RefSeq NP_004951.1; NM_004960.3. [P35637-1]; . UniGene Hs.46894; -; . PDB 2LA6; NMR; -; A=282-370 PDB 2LCW; NMR; -; A=278-385 PDB 4FDD; X-ray; 2.30 A; B=498-526 PDB 4FQ3; X-ray; 3.00 A; B=495-526 PDBsum 2LA6; -; . PDBsum 2LCW; -; . PDBsum 4FDD; -; . PDBsum 4FQ3; -; . DisProt DP01102; -; . ProteinModelPortal P35637; -; . SMR P35637; -; . BioGrid 108797; 336; . DIP DIP-29857N; -; . IntAct P35637; 59; . MINT MINT-5005976; -; . STRING 9606.ENSP00000254108; -; . iPTMnet P35637; -; . PhosphoSitePlus P35637; -; . SwissPalm P35637; -; . BioMuta FUS; -; . DMDM 544357; -; . EPD P35637; -; . PaxDb P35637; -; . PeptideAtlas P35637; -; . PRIDE P35637; -; . TopDownProteomics P35637-1; -. [P35637-1]; . TopDownProteomics P35637-2; -. [P35637-2]; . DNASU 2521; -; . Ensembl ENST00000254108; ENSP00000254108; ENSG00000089280. [P35637-1]; . Ensembl ENST00000380244; ENSP00000369594; ENSG00000089280. [P35637-2]; . GeneID 2521; -; . KEGG hsa:2521; -; . UCSC uc002ebh.4; human. [P35637-1]; . CTD 2521; -; . DisGeNET 2521; -; . GeneCards FUS; -; . GeneReviews FUS; -; . HGNC HGNC:4010; FUS; . HPA CAB033036; -; . HPA CAB058691; -; . HPA HPA008784; -; . MalaCards FUS; -; . MIM 137070; gene; . MIM 608030; phenotype; . MIM 612160; phenotype; . MIM 614782; phenotype; . neXtProt NX_P35637; -; . OpenTargets ENSG00000089280; -; . Orphanet 803; Amyotrophic lateral sclerosis; . Orphanet 275872; Frontotemporal dementia with motor neuron disease; . Orphanet 862; Hereditary essential tremor; . Orphanet 300605; Juvenile amyotrophic lateral sclerosis; . Orphanet 79105; Myxofibrosarcoma; . Orphanet 99967; Myxoid/round cell liposarcoma; . PharmGKB PA28425; -; . eggNOG ENOG410IP58; Eukaryota; . eggNOG ENOG4111GEG; LUCA; . GeneTree ENSGT00530000063105; -; . HOGENOM HOG000038010; -; . HOVERGEN HBG095056; -; . InParanoid P35637; -; . KO K13098; -; . PhylomeDB P35637; -; . TreeFam TF322599; -; . Reactome R-HSA-72163; mRNA Splicing - Major Pathway; . SIGNOR P35637; -; . ChiTaRS FUS; human; . GeneWiki FUS; -; . GenomeRNAi 2521; -; . PRO PR:P35637; -; . Proteomes UP000005640; Chromosome 16; . Bgee ENSG00000089280; -; . CleanEx HS_FUS; -; . ExpressionAtlas P35637; baseline and differential; . Genevisible P35637; HS; . GO GO:0044327; C:dendritic spine head; IEA:Ensembl; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:CACAO; . GO GO:0043204; C:perikaryon; IEA:Ensembl; . GO GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl; . GO GO:0005844; C:polysome; IEA:Ensembl; . GO GO:0003677; F:DNA binding; IEA:UniProtKB-KW; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0000166; F:nucleotide binding; IEA:InterPro; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0003713; F:transcription coactivator activity; IDA:CACAO; . GO GO:0008270; F:zinc ion binding; IEA:InterPro; . GO GO:0071277; P:cellular response to calcium ion; IEA:Ensembl; . GO GO:0000398; P:mRNA splicing; via spliceosome; TAS:Reactome Gene3D 3.30.70.330; -; 1; . Gene3D 4.10.1060.10; -; 1; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . InterPro IPR001876; Znf_RanBP2; . Pfam PF00076; RRM_1; 1; . Pfam PF00641; zf-RanBP; 1; . SMART SM00360; RRM; 1; . SMART SM00547; ZnF_RBZ; 1; . SUPFAM SSF54928; SSF54928; 1; . SUPFAM SSF90209; SSF90209; 1; . PROSITE PS50102; RRM; 1; . PROSITE PS01358; ZF_RANBP2_1; 1; . PROSITE PS50199; ZF_RANBP2_2; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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